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目的:探讨羊水栓塞(AFE)的临床特点及防治措施。方法:选取我院2010年6月份-2012年6月份收治的30例AFE临床资料进行回顾性分析。结果:30例患者都出现了不同程度的呼吸困难、胸闷、呛咳,有部分患者出现了DIC和休克,有9例患者死亡,死亡率为30%。在30例患者中,20例患者使用米苏前列醇和缩宫素。在应用肝素早期的10例患者中,共有1例患者死亡,死亡率为3.33%。结论:在产程中,对于缩宫素和米索前列醇等诱发宫缩的药物,应谨慎、合理使用。对于出现呼吸困难、胸闷等症状而又不明原因的孕产妇,应警惕发生羊水栓塞,在早期应用肝素可以大大提高抢救的成功率。
Objective: To investigate the clinical features and prevention and treatment of amniotic fluid embolism (AFE). Methods: A retrospective analysis of 30 AFE clinical data of our hospital from June 2010 to June 2012 was retrospectively analyzed. Results: Thirty patients had different degrees of dyspnea, chest tightness and choking. Some patients had DIC and shock. Nine patients died and the death rate was 30%. Of the 30 patients, 20 patients used metoprolol and oxytocin. In the early application of heparin in 10 patients, a total of 1 patient died, the mortality rate was 3.33%. Conclusion: In the labor process, the oxytocin and misoprostol induced contractions of drugs, should be cautious and rational use. For breathing difficulties, chest tightness and other symptoms and unexplained maternal, should be vigilant occurred amniotic fluid embolism, heparin in the early application can greatly improve the success rate of rescue.