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目的分析T2DM发生恶性肿瘤的风险因素。方法回顾性分析886例T2DM患者的临床资料,分析其发生恶性肿瘤的风险因素。结果高龄、男性、心血管疾病、病程长、胰岛素治疗、吸烟、饮酒患者发生恶性肿瘤的OR(95%CI)分别为2.651(1.126～6.534)、2.362(1.116～8.884)、5.228(2.664～11.829)、4.382(2.883～9.235)、2.491(1.223～7.534)、1.911(1.022～3.834)、2.388(1.266～5.626),其工作特征(ROC)曲线下面积分别是0.861、0.796、0.930、0.918、0.834、0.782、0.824。结论高龄、男性、心血管疾病、病程长、胰岛素治疗、吸烟、饮酒是T2DM患者发生恶性肿瘤的风险因素。
Objective To analyze the risk factors of malignant tumor in T2DM. Methods The clinical data of 886 T2DM patients were retrospectively analyzed. The risk factors of malignant tumor were analyzed. Results The OR (95% CI) of malignant tumors in aged, male, cardiovascular disease, long course of disease, insulin therapy, smoking and drinking were 2.651 ), 4.382 (2.883-9.235), 2.491 (1.223-7.534), 1.911 (1.022-3.834) and 2.388 (1.266-5.626), respectively. The area under the ROC curve was 0.861, 0.796, 0.930, 0.918 and 0.834, respectively , 0.782,0.824. Conclusions Elderly, male, cardiovascular disease, long course of disease, insulin therapy, smoking and drinking are the risk factors of malignant tumors in T2DM patients.