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目的 分析广州市军队医院收治的SARS病例的临床流行病学特点 ,为防治对策和措施提供科学依据。方法 采用查阅病历、面对面访谈、电话调查及现场调查相结合的方法 ,收集SARS病例流行病学和临床诊治资料 ,利用SPSS软件 10 0分析SARS病例分布特点和恢复期血清IgG抗体情况。 结果 14 7例SARS临床诊断病例中 ,10 9例分布于广州市各个辖区 ,有 38例来自外地 ;发病年龄主要集中在 18~ 4 8岁 ;37例属于聚集性病例 ,4 9例有明确的接触史 (33 33% ) ;死亡 7例。检测 90例恢复期血清特异性IgG抗体 ,阳性 4 6例 ,有同类病例接触史者血清抗体阳性率为 85 2 9% ,高于无接触史者的 2 7 6 6 % (P <0 0 0 1)。发热时间≥ 7d者血清抗体阳性率为 6 8 89% ,高于发热 <7d者的 30 95 % (P <0 0 0 1)。结论 广州军队医院收治的SARS病例流行病学特点与广东省疫情态势基本一致 ;流行病学接触史加血清学结果有助于病例确诊 ;存在未明的传染来源或传播方式。
Objective To analyze the clinical epidemiological characteristics of SARS cases admitted to Guangzhou Military Hospital and provide scientific evidences for prevention and control measures and measures. Methods The epidemiological and clinical diagnosis and treatment data of SARS cases were collected by referring to medical records, face-to-face interviews, telephone surveys and field surveys. The distribution characteristics of SARS cases and serum IgG antibodies in convalescent cases were analyzed by SPSS software. Results Among 147 cases of SARS, 109 cases were found in all districts of Guangzhou City and 38 cases were from other places. The age of onset was mainly between 18 and 48 years old. 37 cases were clustered and 49 cases were definite Contact history (33 33%); death in 7 cases. 90 cases of convalescent serum-specific IgG antibodies were detected, 46 cases were positive, with a positive rate of 85.29% in the same type of cases with history of exposure, which was higher than that of 276.6% (P <0 0 0) 1). The positive rate of serum antibody was 6 8 89% when the fever time was more than 7 days, which was higher than 30 95% (P 0 01) of the fever <7 days. Conclusions The epidemiological characteristics of SARS cases admitted to Guangzhou Military Hospital are basically consistent with those of epidemic situation in Guangdong Province. Epidemiological exposure to history plus serological results is helpful for the diagnosis of cases. There are unknown sources of infection or modes of transmission.