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目的探讨经腹三维超声容积对比成像联合C平面技术(VCI-C)对胎儿小脑蚓部发育异常的诊断价值。方法以2014年1月~2016年6月产前超声检查的4200例孕妇为研究对象,产前超声检查、系统胎儿检查显示疑似小脑蚓部发育异常30例,从剩余正常胎儿中抽取50例为对照组,均接受经腹三维超声容积对比成像联合C平面技术检查,观察胎儿小脑蚓部发育正常、异常声像图表现,测量并比较正常与异常胎儿平均BT、BV。结果 30例疑似小脑蚓部发育异常胎儿经VCI-C检查显示单纯后颅窝池增宽11例,Dandy-Walker变异8例,Blake’s囊肿7例,Dandy-Walker畸形4例,与MRI颅脑正中矢状面检查结果一致。Dandy-Walker变异、Blake’s囊肿、Dandy-Walker畸形胎儿平均BV、BT均显著大于对照组(P<0.05),但单纯后颅窝池增宽与对照组比较无显著差异(P>0.05)。结论经腹三维超声容积对比成像联合C平面技术在胎儿小脑蚓部发育异常诊断中有重要作用。
Objective To investigate the value of three-dimensional ultrasound volume contrast imaging combined with C-plane technique (VCI-C) in the diagnosis of fetal cerebellar vermis dysplasia. Methods 4200 pregnant women with prenatal ultrasound examination from January 2014 to June 2016 were selected as the study objects. Prenatal ultrasound and fetal examination showed that 30 cases were suspected of cerebellar vermis dysplasia, and 50 cases were from the remaining normal fetuses The control group received intra-abdominal three-dimensional ultrasound volume contrast imaging combined with C-plane technique to observe the normal development of fetal cerebellar vermis and abnormal sonogram. The average BT and BV of normal and abnormal fetuses were measured and compared. Results Thirty cases with suspected development of cerebellar vermis were examined by VCI-C. Eleven cases of simple posterior cranial fossa fossa, eight cases of Dandy-Walker variation, seven cases of Blake’s cyst, four cases of Dandy-Walker malformation, The sagittal examination results are consistent. The average BV and BT of Dandy-Walker mutation, Blake’s cyst and Dandy-Walker malformation fetus were significantly higher than those of the control group (P <0.05). However, there was no significant difference between the simple posterior fossa cell enlargement and the control group (P> 0.05). Conclusion The transabdominal three-dimensional ultrasound volume contrast imaging combined with C-plane technique plays an important role in the diagnosis of abnormal development of fetal cerebellar vermis.