论文部分内容阅读
头孢克洛已广泛应用于治疗细菌感染性疾病,临床疗效显著,但其可造成肾脏损害。为此,我科在用头孢克洛治疗小儿细菌性肺炎的同时,在应用前、中、后对患者的尿微蛋白作了测定,结果在2周疗程结束,未发现测定值的差异,表明头孢克洛是安全可靠的。 1 对象和方法 1995年1月～1996年1月,以“细菌性肺炎”收入院治疗的患儿48例,男29例,女19例,年龄1岁～11岁,临床诊断均符合1987年中华人民共和国卫生部小儿肺炎防治方案,病程<2d,未患其它疾病,未用其它药物治疗。用广州南新制药有限公司出品的头孢克洛混悬剂治疗(每瓶60ml,含头孢克洛1.5g),按20mg/(kg·d),q 8h,po,疗程2周。并于治疗前1d及治疗第7天疗程结束后第1天留晨尿作尿微蛋白(Alb,p_2-m,IgG)的RIA,试剂盒由中国原子能研究所提供。
Cefaclor has been widely used in the treatment of bacterial infections, the clinical efficacy of significant, but it can cause kidney damage. To this end, our department in the treatment of bacterial pneumonia with cefaclor in children at the same time, before, during and after the patient’s urine micro-protein was measured in the results of two weeks of treatment ended, no difference was found in the value that Cefaclor is safe and reliable. 1 objects and methods January 1995 ~ January 1996, to “bacterial pneumonia” income hospital treatment of 48 cases of children, 29 males and 19 females, aged 1 to 11 years old, the clinical diagnosis are in line with 1987 People’s Republic of China Ministry of Health prevention and treatment of pediatric pneumonia programs, duration <2d, not suffering from other diseases, no other drug treatment. Treatment with cefaclor suspension (60ml per bottle, containing 1.5g of cefaclor) by Guangzhou Nanxin Pharmaceutical Co., Ltd. at 20mg / (kg · d), q8h, po for 2 weeks. At the first day before treatment and on the seventh day after treatment, the morning urine was collected for RIA of urine microalbumin (Alb, p 2 -m, IgG). The kit was provided by China Institute of Atomic Energy.