论文部分内容阅读
为了评估医生们对药品安全委员会(the committee on Safety of Medicines,CSM)的药物不良反应报告方案所持的态度,作者以信访调查的方式,随机抽取500名英国医师,通过向他们邮寄调查表,并在邀请函发出4周后,再去信提醒他们,结果,共收到285名医师的回信,应答率为57%,应答者中医院医师与开业的通科医师所占比例几乎相等.有65%的应答者称,在某个时候已向CSM或厂家报告过药物不良反应.大多数医师认为严重的不良反应、不常见的反应或与某种新产品有关的不良反应对于他们决定是否投寄报告具有重要的影响,而缺少时间和报告表的可用性(availablity)是妨碍报告的主要因素.害怕承担法律责任、水平欠缺、及资料保密等并未构成报告的制约因素.当作者问及CSM的黑三角(加强监察)方案时,尽管大多数被调
To assess physician attitudes toward the ADR reporting program of the committee on Safety of Medicines (CSM), the authors randomly selected 500 British physicians by mail-order survey by mailing questionnaires to them and Four weeks after the letter was sent out, they were sent a letter reminding them that as a result, a total of 285 doctors responded with a response rate of 57%, and the proportion of Chinese medicine hospital doctors and practicing general practitioners was almost equal. % Of respondents reported that adverse drug reactions had been reported to the CSM or manufacturer at some point.Most physicians considered serious adverse reactions, unusual reactions, or adverse reactions associated with a new product to their decision whether to post The report has a significant impact, while the lack of time and availability of report forms is a major factor hindering the reporting. Fear of legal liability, lack of level, and confidentiality of information does not constitute a reporting constraint .When the author asked CSM When the Black Triangle (Enhanced Surveillance) program was adopted, most were adjusted