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测定３７例消化道肿瘤病人的外周血Ｔ细胞亚群，结果发现术后病人组ＣＤ３和ＣＤ８明显降低（Ｐ＜０．０５）。结肠癌患者ＤｕｋｅｓＡ期ＣＤ４和ＣＤ４／ＣＤ８明显高于正常，Ｐ分别＜０．０１和０．００１；粘液腺癌的病人ＣＤ４／ＣＤ８高于对照。结论：消化道肿瘤病人Ｔ细胞亚群的变化与肿瘤的分期及病理类型有关；手术切除肿瘤有利于细胞免疫功能的恢复。
Determination of peripheral blood T cell subsets in 37 patients with digestive tract tumors revealed a significant reduction in CD3 and CD8 in the postoperative patient group (P<0.05). The CD4 and CD4/CD8 levels in patients with colon cancer were significantly higher than those in normal subjects, with P<0.01 and 0.001, respectively. The patients with mucinous adenocarcinoma had higher CD4/CD8 than controls. Conclusion: The changes of T cell subsets in patients with digestive tract cancer are related to the stage and pathological type of the tumor. Surgical removal of the tumor is beneficial to the recovery of cellular immune function.