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目的研究重组链激酶(rSK)在脑室内出血治疗中的应用。方法对15例重度脑室内出血(IVH),于发病后16小时内进行双侧或单侧脑室外引流术,并辅以rSK脑室内纤溶治疗。结果CT复查示,14例于术后4日脑室内积血减少约60%,7例积血1周内完全消失,7例于2周内消失,1例死亡,随访13例中优良11例,脑积水3例行脑室腹腔分流术。结论早期脑室外引流及应用rSK纤溶治疗重度IVH效果良好,无明显副反应发生。
Objective To study the application of recombinant streptokinase (rSK) in the treatment of intraventricular hemorrhage. Methods Fifteen patients with severe intraventricular hemorrhage (IVH) were treated with bilateral or unilateral ventricular drainage within 16 hours after onset and supplemented with rSK intracerebroventricular fibrinolysis. Results The CT findings showed that in 14 cases, the intracerebral hemorrhage was reduced by 60% on the 4th day after operation. The hemorrhage in 7 cases disappeared completely in 1 week, 7 cases disappeared in 2 weeks, 1 died and 11 cases were followed up , 3 cases of hydrocephalus ventriculoperitoneal shunt. Conclusion Early intraventricular drainage and application of r SK fibrinolytic treatment of severe IVH good effect, no obvious side effects.