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以豚鼠皮肤为材料,用红景天素和鹿血清制成混合制剂(红鹿制剂)进行抗衰老的探讨。以生物化学方法分别测定未经弱酸抽提的和经0.5M醋酸抽提的皮肤胶原中的羟脯氨酸含量。未经弱酸抽提的每毫克皮肤的羟脯氨酸含量为:对照组37.166±5.728μg;给药组42.222±6.077μg;经0.5M醋酸抽提的每毫克皮肤的羟脯氨酸含量为:对照组3.935±0.232μg,给药组5.528±2.848μg。经统计学检验,用醋酸抽提的胶原数量在给药组和对照组间有显著性差异(P<0.05)。提示红鹿制剂能促使皮肤中老化性架桥的数量相对减少。
Using guinea pig skin as material, we studied the anti-aging effect of the mixture of Rhodiola and deer serum (red deer preparation). The content of hydroxyproline in skin collagen extracted without weak acid and extracted with 0.5M acetic acid were determined biochemically. Hydroxyproline content per milligram of skin without weak acid extraction was: 37.166 ± 5.728 μg in the control group; 42.222 ± 6.077 μg in the dosing group; and per milligram of skin extracted with 0.5 M acetic acid Hydroxyproline content: control group 3.935 ± 0.232μg, administration group 5.528 ± 2.848μg. Statistically, there was a significant difference in the amount of collagen extracted with acetic acid between the administration group and the control group (P <0.05). Tip Red deer preparations can promote the skin to reduce the number of aging bridges.