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目的 提高口腔颌面外科医生对蓝色橡皮大疱样痣综合征的认识和鉴别。方法 报告1例蓝色橡皮大疱样痣综合征合并口腔颌面部血管瘤的典型病例,并复习了26篇相关文献。结果 蓝色橡皮大疱样痣综合征病例约59％～64％合并口腔颌面部海绵状血管瘤及其它部位皮肤蓝色血管瘤。结论 对口腔颌面部海绵状血管瘤同时伴有四肢或躯于部位皮肤蓝色血管瘤的病人,口腔科医生要注意鉴别是否患有蓝色橡皮大疱样痣综合征的可能。该综合征虽然少见,但时刻潜在着消化道致命性大出血的危险。
Objective To improve the recognition and identification of blue rubber bullous nevus syndrome by oral and maxillofacial surgeons. Methods A typical case of blue rubber bullous syndrome associated with oral and maxillofacial hemangioma was reported and 26 related articles were reviewed. RESULTS: About 59% to 64% of blue rubber bullous nevus syndrome combined with oral and maxillofacial cavernous hemangiomas and other parts of the skin blue hemangiomas. Conclusions For oral and maxillofacial cavernous hemangioma patients accompanied by blue-angulated hemangiomas of the limbs or the body at the same time, the dentist should pay attention to identify the possibility of suffering from blue rubber bullous nevus syndrome. Although rare, the syndrome is potentially at risk for fatal bleeding in the digestive tract.