论文部分内容阅读
目的探讨宫颈特殊染色法(FRD)用于宫颈癌前病变检测的价值。方法 1000例行宫颈疾病筛查的妇女作为检测对象,先后使用FRD、液基薄层细胞学技术(TCT)、人乳头瘤病毒(HPV)三种方法检查,分析三种不同检测方法灵敏度、特异度、阳性预测值、阴性预测值。结果 1000例中经阴道镜检查活检确诊阳性病例37例,其中行FRD检测出阳性病例46例,病理确诊24例;TCT检测出阳性病例44例,病理确诊21例;HPV检出阳性病例114例,病理确诊33例。FRD与TCT检测阳性预测值、阴性预测值、灵敏度、特异度比较,差异无统计学意义(P>0.05)。FRD检测阳性预测值及特异度高于HPV检测,阴性预测值、灵敏度低于HPV检测,差异均具有统计学意义(P<0.05)。结论 FRD与TCT检测的效果相当,其阳性预测值及特异度高于HPV检测,虽然阴性预测值及灵敏度较HPV检测低,但FRD检测操作简便,能很快得到结果 ,成本低廉,具有较高的临床检测价值,值得推广。
Objective To investigate the value of cervical special staining (FRD) in the detection of cervical precancerous lesions. Methods A total of 1000 women who underwent screening for cervical diseases were tested by FRD, TCT and HPV tests. The sensitivity and specificity of three different detection methods were analyzed. Degree, positive predictive value, negative predictive value. Results Thirty-seven cases were confirmed by colposcopy biopsy in 1000 cases, of which 46 cases were positive by FRD, 24 cases were confirmed by pathology, 44 cases were positive by TCT, 21 cases were pathologically confirmed, and 114 cases were positive by HPV Pathological diagnosis of 33 cases. There was no significant difference between the positive predictive value, negative predictive value, sensitivity and specificity of FRD and TCT (P> 0.05). The positive predictive value and specificity of FRD test were higher than those of HPV test, negative predictive value and sensitivity lower than HPV test (P <0.05). Conclusion The results of FRD and TCT are equivalent, the positive predictive value and specificity are higher than that of HPV test. Although the negative predictive value and sensitivity are lower than those of HPV test, the FRD test is simple and easy to operate, the results are fast, the cost is low, and the cost is high. The clinical test value, it is worth promoting.