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为观察铅对海马区长时程增强过程中蛋白激酶Ｃ（ＰＫＣ）活性的影响，用０．１％醋酸铅喂养大鼠３个月后，在高频刺激下诱发海马齿状回产生长时程增强，测定ＰＫＣ活性。结果：与对照组比较，细胞浆和细胞膜的ＰＫＣ活性明显升高（Ｐ＜０．００１）。提示：ＰＫＣ在铅干扰长时程增强中起关键性作用。
To observe the effect of lead on protein kinase C (PKC) activity during long-term potentiation in hippocampus, rats were fed with 0.1% lead acetate for 3 months and then induced by high frequency stimulation. Enhancement, determination of PKC activity. Results: Compared with the control group, the PKC activity of cytoplasm and cell membrane was significantly increased (P <0.001). Tip: PKC plays a key role in long-term potentiation of lead interference.