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目的试图在近年疟疾发病率已降至零的海南山区搜索残余疟疾病人,以检验当地疟疾发病率降至零的可靠性,为评估海南省消除疟疾的进展提供参考。方法选择海南东南部原高疟山区万宁市南桥镇以及三更罗镇的两个行政村及其邻近的南林农场和新中农场的三个作业区,以经常上山住宿的高危人群作为调查检测对象,同时采用两种检测方法,即疟疾快速诊断试验(RDT)和聚合酶链反应(PCR)进行检测。结果总共调查检测480人,PCR检测全部为阴性;RDT检测发现两例间日疟阳性反应。但经厚血膜镜检复查均为阴性,予以否定。结论调查结果从一个个侧面证实当地疟疾传播确已下降至很低的水平,对当地发病率监测结果提供了有力的支持,从而为海南省消除疟疾的评估提供了参考。
Objective To search for residual malaria patients in the mountainous areas of Hainan Province where the incidence of malaria has dropped to zero in recent years in order to test the reliability of reducing the incidence of malaria to zero in the local area and provide a reference for assessing the progress of malaria elimination in Hainan Province. Methods Three operating areas in Nanqiao Town of Wanning City and the two administrative villages in Sanjianluo Town and the adjacent Nanlin Farm and Xinzhong Farm in southeastern Hainan were selected as the high risk population who often stay in the mountains Investigate the test subjects, using two detection methods, namely rapid malaria diagnostic test (RDT) and polymerase chain reaction (PCR) for detection. RESULTS: A total of 480 individuals were tested and all PCR tests were negative. RDT test found positive reaction between the two cases. However, by thick film microscopy examination were negative, to be rejected. Conclusion The results of the survey confirm that the spread of malaria in the local area has indeed dropped to a very low level from one side and provided strong support for the monitoring results of local morbidity. This provides a reference for the assessment of malaria elimination in Hainan Province.