目的　探求在保护下丘脑功能的条件下 ,安全地全切或近全切儿童颅咽管瘤。方法　采用经胼胝体 透明隔间隙 穹隆间入路、经额部纵裂入路等方法 ,手术切除儿童颅咽管瘤 10 5例。术前和术后采取积极措施预防和治疗下丘脑功能紊乱。结果　全切 +近全切 96例 (91 4% ) ,死亡 1例(1 0 % )。术后主要并发症为 :尿崩症 (93 3% )、血电解质紊乱 (89 5 % )和癫痫 (3 8% ) ,癫痫为致命性的并发症。结论　术前、术中和术后保护下丘脑功能是近可能全切除肿瘤的先决条件 ,手术一定要在直视下切除肿瘤 Objective To explore in the protection of hypothalamic function of the condition, safely cut or near total cut children craniopharyngioma. Methods 105 cases of craniopharyngioma were excised surgically by translumenal translumenal approach of the corpus callosum and transurethral approach. Preoperative and postoperative take active measures to prevent and treat hypothalamic dysfunction. Results Total and near complete resection in 96 cases (91 4%), death in 1 case (10%). The main postoperative complications were diabetes insipidus (93.3%), blood electrolyte disturbance (89.5%) and epilepsy (38%), and epilepsy was a fatal complication. Conclusions Preoperative, intraoperative and postoperative protection of hypothalamic function is a prerequisite for complete resection of the tumor, the surgery must be under direct vision to remove the tumor