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一推广HPV DNA检测技术的意义宫颈癌的发生与人乳头瘤病毒(HPV)密切相关。大量的研究结果显示,在宫颈浸润癌中HPV DNA的检出率几乎为100%,在宫颈癌前病变中HPV的检出率为75%~100%[1]。目前,世界范围内90%的宫颈癌是由HPV16、18、45、31、33、52、58和35所导致的,因此这些亚型又被称为高危型HPV。其中与宫颈癌最密切相关的亚型为HPV16和18,它们可导致50%的宫颈上皮内瘤变II(CIN2),70%的CIN3和宫颈癌,感染HPV16/18(+)发展为宫颈癌前病变的风险
A promotion of HPV DNA detection of significance Cervical cancer and human papillomavirus (HPV) is closely related. A large number of studies have shown that the detection rate of HPV DNA in cervical invasive carcinoma is almost 100%, and the detection rate of HPV is 75% -100% in cervical precancerous lesions [1]. Currently, 90% of cervical cancers worldwide are caused by HPV types 16, 18, 45, 31, 33, 52, 58 and 35, and these subtypes are also known as high-risk HPV types. Among them, the most closely related subtypes of cervical cancer are HPV16 and HPV18, which cause 50% of cervical intraepithelial neoplasia II (CIN2), 70% of CIN3 and cervical cancer, and HPV16 / 18 (+) infection develop cervical cancer Risk of pre-lesion