喉癌通常沿着粘膜表面或粘膜下扩散。颈部皮肤浸润较少见。作者报道12例直接侵犯颈部皮肤并呈蕈样生长的喉癌患者。6例初发病灶行深部X线根治性放疗,其中5例作环状软骨下的高位气管切开术。部分喉切除3例,其中2例为前外侧喉切除术,另1例为声门上区喉切除术;有2例颈部皮肤感染行切开引流。全部病例在初治1～12月后局部复发,浸润皮肤呈蕈样生长。这些病例的再治方法是;全喉切除11例,1例作全咽切除,所有患者均用皮瓣修复缺损部位,其中1例修复咽和口底。结果:2例患者分别死于全喉切除术后8和18 Laryngeal cancer usually spreads along the mucosal surface or submucosally. Neck skin infiltration is less common. The authors reported 12 patients with laryngeal cancer who directly invaded the neck skin and presented with spasmodic growth. Six cases of primary lesions underwent radical X-ray radiotherapy, of which 5 cases underwent high tracheotomy under the cricoid cartilage. Partial laryngectomy was performed in 3 cases, including 2 cases of anterolateral laryngectomy, and 1 case of supraglottic laryngectomy; 2 cases of neck skin infection were incised and drained. All cases had local recurrence after the initial treatment from January to December, and the infiltrated skin showed a growth like a sputum. The retreatment methods for these cases were: total laryngectomy in 11 cases, and 1 case for total pharyngectomy. All patients were treated with flaps to repair the defect site, and 1 case was repaired to the pharynx and the floor of the mouth. Results: Two patients died of total laryngectomy 8 and 18, respectively