南阳市区学生麻疹风疹抗体水平调查分析

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目的了解南阳市区学生麻疹风疹抗体水平。方法依照国家级麻疹监测点方案,按照比例容量法随机抽样方法进行调查、统计分析。结果共调查1 155人,麻疹抗体阳性率97.23%、风疹抗体率90.65%;其中学生麻疹抗体阳性率98.46%、风疹抗体率83.95%;社会人群麻疹抗体阳性率96.75%、风疹抗体阳性率93.26%。学生和社会人群的麻疹抗体阳性率无显著性差异(P>0.05),风疹阳性率有显著性差异(P<0.05);两组的麻疹、风疹抗体阳性率均有显著性差异(P<0.05)。学生麻疹抗体滴度、风疹抗体滴度(lg)分别为(-0.101±0.299)m IU/m L、(1.589±0.630)IU/m L;社会人群的麻疹抗体滴度、风疹抗体滴度(lg)分别为0.023±0.459 IU/m L0、(1.802±0.493)m IU/m L,学生与社会人群的麻疹抗体滴度、风疹抗体滴度均有显著性差异(P<0.05)。学生和社会人群有麻疹或风疹患病史的率有显著性差异,社会人群显著高于学生人群(P<0.05)。结论学生是高度聚集的人群,容易出现麻疹和风疹的局部暴发、流行,针对学生进行麻疹类疫苗的复种,减麻疹风疹散发病例和学校的暴发疫情,也可维持人群有较高的抗体水平。 Objective To understand the measles and rubella antibody levels of students in downtown Nanyang. Methods According to the national measles monitoring program, the random sampling method was used to carry out surveys and statistical analyzes. Results A total of 1 155 people were investigated. The positive rate of measles antibody was 97.23% and the rate of rubella antibody was 90.65%. The positive rate of measles antibody was 98.46% and the rate of rubella antibody was 83.95%. The positive rate of measles antibody in community was 96.75% and the positive rate of rubella antibody was 93.26% . The positive rate of measles antibody was not significantly different between students and social groups (P> 0.05), and the positive rate of rubella was significantly different (P <0.05). The positive rates of measles and rubella antibody in both groups were significantly different (P <0.05 ). Measles antibody titers and rubella antibody titers (lg) were (-0.101 ± 0.299) m IU / m L and (1.589 ± 0.630) IU / m L, respectively. Measles antibody titers and rubella antibody titers lg) were 0.023 ± 0.459 IU / m L0 and (1.802 ± 0.493) mIU / m L, respectively. There were significant differences in measles antibody and rubella antibody titers between students and the general population (P <0.05). There was a significant difference in the history of measles or rubella among students and social groups, and the social population was significantly higher than that of the students (P <0.05). Conclusions Students are highly clustered and prone to local outbreaks and epidemics of measles and rubella. They can also maintain the high antibody level in the population in response to the students’ repeated vaccination of measles vaccine, measles-eradication cases and school outbreaks.
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