答:血栓性疾病是致死、致残的主要病因之一,血栓形成和血栓栓塞是心脑血管事件的主要发病机制之一,循证医学证据表明规范的抗栓治疗能明显降低血栓和血栓栓塞事件的发生。虽然近年来有Ⅱa因子抑制剂的开发,但目前华法林仍然是惟一的有大量循证证据的口服抗凝药,研究证实,华法 A: Thrombotic diseases are one of the major causes of death and disability. Thrombosis and thromboembolism are one of the major pathogenesis of cardiovascular and cerebrovascular events. Evidence-based medical evidence indicates that standard antithrombotic therapy can significantly reduce thrombus and thromboembolism Occurrence of the incident. Although the development of Factor IIa inhibitors has been developed in recent years, warfarin is still the only oral anticoagulant with a large evidence base of evidence. Studies have shown that warfarin