器官缺血/再灌注(ischem ia/reperfusion,I/R)时,由于机体氧化系统和抗氧化系统失衡,氧自由基(reactive oxygen species,ROS)产生增多,在体内蓄积过多,使器官组织的细胞膜脂质过氧化,细胞线粒体受损,引起组织细胞凋亡和坏死,造成器官组织损伤[1]。器官I/R导致的损伤实际上是一 In organ ischemia / reperfusion (I / R), the production of reactive oxygen species (ROS) is increased due to the imbalance between the body’s oxidative system and the antioxidant system. In the body, excessive accumulation of organ oxygen Lipid peroxidation of the cell membrane, damaged mitochondria, causing apoptosis and necrosis of tissues, resulting in organ tissue damage [1]. The damage caused by organ I / R is actually one