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单核细胞趋化蛋白-1(monocyte che-moattractant protein-1,MCP-1/CCL2)是重要的趋化因子之一,在体内外具有强大的诱导单核/巨噬细胞聚集、附壁、游走的功能。近年来,MCP-1对心血管疾病的作用及其机制日益受到人们的广泛关注,本文就对MCP-1在心血管疾病中的研究进展做一综述。
Monocyte chemoattractant protein-1 (MCP-1 / CCL2) is one of the important chemokines and has strong in vitro and in vivo induction of monocyte / macrophage aggregation, Walk the function. In recent years, the effect of MCP-1 on cardiovascular diseases and its mechanism has been paid more and more attention by people. This article reviews the research progress of MCP-1 in cardiovascular diseases.