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本文研究了奥丹西酮在不同电流密度下经小鼠全皮的渗透动力学。当电流密度从0.05mA．cm-2升高到0.3mA．cm-2时，药物的稳态流量从30．29μg．cm-2.h-1增加到160.70μg．cm-2.h-1。研究中药物稳态流量和应用电流之间不严格呈线性关系。铂在供药池中作阳极时，可导致药物溶液变色；而应用银电极代替铂电极，则可以避免此问题的出现。应用铂电极时，供药池和接受池中均发现有pH变化。文章对以上问题以及解决的方法进行了讨论。
In this paper, osmotic dynamics of ondansetron in whole-skin of mice was studied under different current densities. When the current density is from 0.05mA. cm-2 to 0.3mA. cm-2, the steady-state flow of the drug was from 30.29 μg. cm-2.h-1 to 160.70 μg. cm-2.h-1. There is no strict linear relationship between the steady-state flow of the drug and the applied current. Platinum in the drug pool for the anode, can lead to drug solution discoloration; and the use of silver electrode instead of platinum electrode, you can avoid this problem. When using platinum electrodes, there is a change in pH found in both the drug reservoir and the receiving reservoir. The article discusses the above problems and the solutions.