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1关键词:瑞替加滨Potiga(依佐加滨Ezogabine)视网膜异常皮肤蓝色脱色反应04/26/2013FDA警示:抗癫痫药物瑞替加滨(依佐加滨)可引起皮肤蓝色脱色反应和以视网膜颜色变化为特征的眼部异常。FDA尚不清楚上述变化是否可逆。视网膜色素改变会导致严重眼部疾病甚至失明。虽然已有几名患者视力受损的报告,但目前尚不能确定是由于瑞替加滨导致视网膜色素改变引起的。已报告病例的皮肤异常表现为蓝色色素
1 Keywords: Retigabine Potiga (Ezogabine) Retinal Abnormal Skin Blue Decolorization 04/26/2013 FDA Warning: The antiepileptic drug retigabine (izogamubin) causes a blue-bleaching reaction to the skin And ocular abnormalities characterized by changes in the color of the retina. FDA is not clear whether the above changes are reversible. Retinal pigment changes can cause serious eye disease or even blindness. Although there are several reports of impaired vision in patients, it is not yet known that retigabine causes retinal pigment changes. Skin abnormalities have been reported as blue pigment in the reported cases