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[目的]分析辽宁省城市2000~2011年间甲状腺癌发病率和死亡率现状及变化趋势。[方法 ]采用辽宁五市肿瘤登记处数据,计算年龄别发病率和死亡率、世界人口标化率及其年度变化百分比(annual percent change,APC)。[结果]五城市居民甲状腺癌发病世标率为4.14/10万,死亡世标率为0.33/10万。2000~2011年甲状腺癌发病世标率APC为16.55%(α=0.05,P<0.05),死亡世标率APC为-2.08%(α=0.05,P>0.05)。2011年大连市男女发病世标率分别为12.94/10万和36.31/10万,为其他城市的8.78~16.18倍;男女死亡世标率分别为0.30/10万和0.46/10万。大连市发病世标率APC为22.32%(α=0.05,P<0.05),死亡世标率APC为0.37%(α=0.05,P>0.05)。[结论 ]辽宁城市居民甲状腺癌发病和死亡水平及其变化趋势与国内其他地区相近。大连市甲状腺癌发病率及其增速高于辽宁省其他城市和国内其他地区,甲状腺癌筛查和影像技术普及应用可能是导致当地近些年发病率持续快速升高的主要原因,应进一步提高甲状腺癌筛查和诊疗的规范性。
[Objective] To analyze the status and changing trend of morbidity and mortality of thyroid cancer from 2000 to 2011 in Liaoning Province. [Methods] Based on the data of Liaoning Province Five Tumor Registry, the age-related morbidity and mortality, world population standardization rate and its annual percent change (APC) were calculated. [Results] The incidence rate of thyroid cancer in five urban residents was 4.14 / 100,000 and the death rate was 0.33 / 100,000. The APC of incidence of thyroid cancer from 2000 to 2011 was 16.55% (α = 0.05, P <0.05). The death rate of APC was -2.08% (α = 0.05, P> 0.05). In 2011, the prevalence rates of male and female incidences in Dalian were 12.94 / lakh and 36.31 / lakh, respectively, which were 8.78-16.16 times higher than those in other cities. The rates of deaths of males and females were 0.30 / lakh and 0.46 / lakh, respectively. The incidence rate of APC in Dalian was 22.32% (α = 0.05, P <0.05), and the death rate was APC 0.37% (α = 0.05, P> 0.05). [Conclusion] The incidence and mortality of thyroid cancer in Liaoning urban residents are similar to those in other areas in China. The incidence of thyroid cancer in Dalian and its growth rate are higher than other cities in Liaoning Province and other areas in China. The popularization and application of thyroid cancer screening and imaging technology may be the main reason leading to the sustained and rapid increase of local incidence in recent years and should be further improved Normative thyroid cancer screening and diagnosis.