目的　摸清辽宁省地方性氟中毒病区类型、病区分布、流行特点以及相关影响因素。方法　采取普查与抽样相结合的调查方式。结果　辽宁省地方性氟中毒以饮水型为主 ,病区分布广、危害重。全省氟斑牙患者 6453 87人 ,氟骨症患者 450 78人 ,分布 13个市 ,49个县 ,2 70 5个村屯。病区类型复杂 ,可分为山地丘陵型、平原型、沿海型、温泉型、盆地型。结论　富氟环境是病区形成主要原因。应根据特殊的地理环境及经济条件 ,采取综合防治措施。防氟改水应是辽宁省防治地方性氟中毒的主要措施之一 Objective To find out the types of endemic fluorosis in Liaoning Province, ward distribution, epidemiological characteristics and related factors. Methods A survey method combining census and sampling was adopted. Results In Liaoning Province, endemic fluorosis was mainly water type, with wide distribution and serious harm. 6453 87 dental fluorosis patients and 450 78 skeletal fluorosis patients were distributed in 13 cities, 49 counties and 2 705 villages. Ward complex type can be divided into mountain hilly type, plain type, coastal type, hot spring type, basin type. Conclusion Fluorine-rich environment is the main reason for the formation of ward. Should be based on special geographical environment and economic conditions, to take comprehensive prevention and control measures. Anti-fluoride water should be one of the major measures to prevent and control endemic fluorosis in Liaoning Province