论文部分内容阅读
用亲水凝胶制备的智能型给药系统可以感觉外部条件变化产生的脉冲信号，并判断信号的强度，脉冲式释放相应量药物，实现了外部调控给药。本文综述了由外部化学物质、pH、温度、电场控制的脉冲式给药系统的研究及其药物释放机制。
The intelligent drug delivery system prepared with hydrophilic gel can sense the pulse signal generated by the change of external conditions and determine the intensity of the signal to release the corresponding amount of drug in a pulsed manner to achieve external regulation and administration. This review summarizes the pulsed drug delivery system controlled by external chemicals, pH, temperature and electric field and its drug release mechanism.