多发性硬化（MS）、重症肌无力（MG）、格林巴利综合征（GBS）及急性脊髓炎均是神经内科常见的自身免疫性疾病，过去用常规剂量类固醇疗法见效慢、用药时间长、副作用大、且疗效大多不能令人满意。近6年来我们借鉴国外经验采用大剂量甲基泼尼松龙冲击疗法（MPPT）治疗神经免疫 Multiple sclerosis (MS), myasthenia gravis (MG), Guillain-Barre syndrome (GBS) and acute myelitis are all common autoimmune diseases in neurology. In the past, the effect of conventional steroid therapy was slow, and medication took a long time. Side effects, and most of the efficacy is not satisfactory. Nearly 6 years we learn from foreign experience using high-dose methylprednisolone impact therapy (MPPT) for the treatment of neuroimmunity