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用化学发光法(CL)检测了4组患者和正常对照组吞噬细胞的吞噬功能;进行了吞噬细胞吞噬功能CL峰值/10~3白细胞,体内吞噬细胞预激活状态(本底),血浆调理活性的比较。结果肾移植术后肾功能良好的受者CL峰值/10~3白细胞与正常组比较无显著差异(P>0.05)。术后肾功能较差的受者、未移植透析的患者和术后因排异已切除移植肾的患者CL峰值/10~3白细胞与正常组有显著差异(P<0.05),本底水平比正常对照组显著升高,峰时与正常组无差异。结果表明,肾移植术后吞噬功能的增强,体内预激活状态增高,预示着肾功能减退、排异出现。这一结果对诊断肾移植术后排异具有一定的参考价值。
The phagocytic function of phagocytes in four groups of patients and the normal control group was detected by chemiluminescence method (CL). Phagocyte phagocytosis (CL) peak / 10-3 leukocytes, in vivo phagocyte preactivation state (background), plasma conditioning activity Comparison. Results There was no significant difference in peak CL / 10 ~ 3 leukocytes between recipients with renal function after renal transplantation and normal controls (P> 0.05). There was a significant difference (P <0.05) between peak CL / 10-3 leukocyte count and normal group in patients who had poor postoperative renal function, non-transplant dialysis patients, and postoperative patients with rejection of transplant kidney. The normal control group was significantly increased, no difference between the peak and the normal group. The results show that phagocytosis after renal transplantation enhanced body pre-activation status increased, indicating a decline in renal function, rejection appeared. This result has some reference value for the diagnosis of rejection after renal transplantation.