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世界上一切事物都在运动,它不断推动事物的发展。药物进入机体后,也不断在变化,它通常经血液分布,最后以特殊方式消除。药物的消除包括机体对药物的化学变化(或称代谢)和排泄。消除的速率与程度虽同药物的理化性质与用法以及同通过细胞膜屏障能力,和血浆蛋白结合效率等因素有关,但与肝肾功能关系尤为密
Everything in the world is moving, and it constantly promotes the development of things. After the drug enters the body, it is constantly changing, it is usually distributed through the blood, and finally eliminated in a special way. Drug elimination includes the body’s chemical changes (or metabolism) and excretion of drugs. Although the rate and extent of elimination with the physical and chemical properties of drugs and usage and with the ability to pass through the cell membrane barrier, and plasma protein binding efficiency and other factors, but with liver and kidney function is particularly closely related