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采用基因重组技术构建了两种杂合基因,经大肠杆菌表达产生的两种杂合蛋白含有恶性疟原虫(P.f.)红内期抗原SERP,HRPII或MSAI的部分序列,对这两种蛋白的免疫原性和免疫保护性进行了研究。
Two heterozygous genes were constructed by gene recombination. The two hybrid proteins expressed in Escherichia coli contain the partial sequence of SERP, HRPII or MSAI of Plasmodium falciparum (Pf) Prototrophy and immunoprotection were studied.