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经 ＲＴ－ＰＣＲ证实，趋化性细胞因子 ＭＩＰ－２（巨噬细胞炎症蛋白 ２）不仅表达于小鼠腹腔巨噬细胞，亦表达于新鲜培养的小鼠胸腺基质细胞，且小鼠 ＤＮ，ＤＰ，ＣＤ４ＳＰ和ＣＤＳＳＰ ４个胸腺细胞亚群也不同程度表达其特异受体ＣＸＣＲ２．通过Ｂｏｙｄｅｎ小室趋化实验证实，重组小鼠ＭＩＰ－２对胸腺细胞４个主要亚群有不同强度的趋化作用，主要趋化ＤＰ和ＳＰ胸腺细胞正群，从而报道了ＭＩＰ－２参与诱导胸腺细胞发育过程中的定向迁移．
It was confirmed by RT-PCR that the chemotactic cytokine MIP-2 (macrophage inflammatory protein 2) was not only expressed in murine peritoneal macrophages but also in freshly cultured mouse thymocytes, and the mouse DN, DP , 4 thymocyte subsets of CD4SP and CDSSP also express CXCR2, which is its specific receptor, to varying degrees. Through Boyden chamber chemotaxis assay, MIP-2 recombinant mouse MIP-2 chemotactic effect on the four major subpopulations of thymocytes, mainly chemotaxis DP and SP thymocyte positive group, reported that MIP-2 involved in the induction of thymus Directional migration during cell development.