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手术和放疗是目前治疗头颈癌的最有效方法,但对晚期癌肿疗效仍较差。已有学者报告同时应用顺铂和氟脲嘧啶进行灌注治疗可提高疗效。作者等将71名接受过这种化疗的病人,按治疗顺序不同分成两组,其病人情况大致相同。第一组42人,化疗+手术+放疗。第二组29人,手术+化疗+放疗。化疗共三个疗程,每个疗程用顺铂一天,剂量100mg/m~2,氟脲嘧啶连用五天,剂量1000mg/m~2。第二组术后4周开始化疗,化疗完成后再放疗。作者等将对化疗的反应分为三种:①完全有效(CR),病变和症状完全消失;②部分有效
Surgery and radiotherapy are currently the most effective methods for the treatment of head and neck cancer, but the efficacy of advanced cancer is still poor. Some scholars have reported that the simultaneous application of cisplatin and fluorouracil infusion therapy can improve the efficacy. The author et al. divided the 71 patients who received this chemotherapy into two groups according to the treatment sequence. The patient’s condition was approximately the same. The first group of 42 people were treated with chemotherapy + surgery + radiotherapy. The second group consisted of 29 patients undergoing surgery + chemotherapy + radiotherapy. A total of three courses of chemotherapy, each course of treatment with cisplatin, a dose of 100mg/m~2, fluorouracil used in conjunction for five days, a dose of 1000mg/m~2. The second group started chemotherapy 4 weeks after the operation, and then radiotherapy after the completion of chemotherapy. Authors and others will divide the response to chemotherapy into three types: 1 completely effective (CR), lesions and symptoms completely disappear; 2 part effective