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目的 探讨肝硬化患者中消化性溃疡的发生情况及可能机制。方法 对２４９ 例肝硬化并行胃镜检查的患者进行临床分析。结果 肝硬化患者合并消化性溃疡发生率为４２－２ ％ （１０５／２４９） 。其发生与肝功能Ｃｈｉｌｄ－ Ｐｕｇｈ 分级、食管静脉曲张程度间均显著相关，与幽门螺杆菌感染则无相关关系。结论 肝硬化患者消化性溃疡发病率高，其发病机理值得进一步探讨。
Objective To investigate the occurrence and possible mechanism of peptic ulcer in patients with liver cirrhosis. Methods Clinical data of 249 patients with liver cirrhosis undergoing gastroscopy were analyzed. Results The incidence of peptic ulcer in patients with cirrhosis was 42-2% (105/249). Its occurrence and liver function Child-Pugh grading, esophageal varicose veins were significantly related, and Helicobacter pylori infection was not related. Conclusions The incidence of peptic ulcer in patients with cirrhosis is high, and its pathogenesis deserves further exploration.