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自从1998年12月美国国家健康研究大会正式认可非酒精性脂肪性肝炎(NASH)的重要地位,人们对儿童非酒精性脂肪性肝病(NAFLD)的认识不断增加。随着对疾病的认识、诊断及相关合并症的理解程度的不断加深,将来面临的挑战主要以临床管理为中心。本文将就其重要临床相关问题的最新进展作一简要回顾。一、儿童NAFLD与肝脏生化指标(一)血清谷丙转氨酶(ALT)正常上限是什么?ALT是
Recognition of childhood non-alcoholic fatty liver disease (NAFLD) has been increasing since the National Conference on Health Research formally recognized the importance of non-alcoholic steatohepatitis (NASH) in December 1998. As the understanding of disease, diagnosis and related complications continue to deepen, the challenges in the future are mainly clinical management. This article will provide a brief review of recent advances in its clinically important issues. A child with NAFLD and liver biochemical indicators (a) serum alanine aminotransferase (ALT) What is the normal upper limit? ALT is