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目的调查医院门诊癌症患者麻醉性镇痛药的利用情况,为临床合理使用麻醉性镇痛药提供依据。方法统计医院2008年门诊晚期癌症患者麻醉性镇痛药品处方172张,了解常用药品及其用法、用量,并计算药物利用指数(DUI)。结果常用麻醉性镇痛药共计4种,使用频率为盐酸哌替啶注射液50%,硫酸吗啡控释片(美施康定)43.6%,磷酸可待因片4.65%,盐酸哌替啶片1.74%。3个主要品种的药物利用指数为盐酸哌替啶注射液0.63,硫酸吗啡控释片0.24,磷酸可待因片0.49。调查结果显示我院门诊癌症患者麻醉性镇痛药的利用指数均小于1,而两种药物的利用指数小于0.5。结论医院门诊麻醉性镇痛药用于晚期癌痛病人剂量不足,提示医生对晚期癌痛病人应给足剂量并注意个体化给药方案的实施.
Objective To investigate the utilization of narcotic analgesics in hospital outpatient cancer patients and provide the basis for the rational use of narcotic analgesics. Methods Statistics 172 hospitalized patients with advanced cancer in 2008 anesthesia analgesics prescription 172, to understand the commonly used drugs and their usage, dosage, and calculate the drug utilization index (DUI). Results A total of 4 commonly used narcotic analgesics were used. The frequency of use was 50% of the pethidine hydrochloride injection, 43.6% of the controlled release tablets of morphine sulfate, 4.65% of the codeine phosphate tablets, 1.74% of the pethidine hydrochloride tablets %. The drug utilization indices of the three main varieties were 0.63 for meperidine hydrochloride injection, 0.24 for morphine sulfate controlled release tablets and 0.49 for codeine phosphate tablets. The survey results show that the utilization index of narcotic analgesics in outpatient cancer patients in our hospital is less than 1, while the utilization index of the two drugs is less than 0.5. Conclusion The hospital outpatient anesthesia analgesics are used in patients with advanced cancer pain, which indicates that doctors should give full dose to patients with advanced cancer pain and pay attention to the implementation of individualized drug delivery plans.