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目的:评价口腔植入术围手术期预防用抗菌药物干预前后的用药情况。方法:选取2012年5月—2013年8月间牙科行口腔种植体植入术的患者86例,将其随机分为干预组(n=43)和对照组(n=43),两组患者术前均给予常规预防感染治疗,干预组患者术后给予克林霉素预防感染治疗,对照组患者术前及术后均未给予抗生素预防感染;评价两组患者术后感染发生情况及上、下颌骨种植体存留情况,并作一对比。结果:干预组患者术后感染的发生率为4.65%,明显低于对照组16.28%(P<0.05);两组患者术后上下颌骨种植体存留率经比较其差异无统计学意义(P>0.05)。结论:口腔植入术围手术期预防用抗菌药物的干预,可有效降低种植体植入患者术后感染的发生率,有利于促进创口愈合。
OBJECTIVE: To evaluate the use of antimicrobial agents before and after perioperative prophylaxis of oral implants. Methods: Totally 86 patients who underwent oral dental implants between May 2012 and August 2013 were randomly divided into intervention group (n = 43) and control group (n = 43). The patients in both groups All patients were given routine preventive infection before operation. Patients in intervention group were given clindamycin to prevent infection after operation. Patients in control group were not given antibiotics to prevent infection before and after operation. The incidence of postoperative infection in both groups was evaluated, Mandibular implant retention, and make a comparison. Results: The incidence of postoperative infection in the intervention group was 4.65%, which was significantly lower than that in the control group (16.28%, P <0.05). There was no significant difference in postoperative survival rate between the two groups > 0.05). Conclusion: Perioperative intervention with oral antibiotics can reduce the incidence of postoperative infection in implants and promote wound healing.