人疱疹病毒Ⅰ型 (ＨＨＶ 1)糖蛋白Ｂ是一种跨膜糖蛋白 ,其前体分子含 90 4个氨基酸。根据病毒株的不同 ,Ｎ端的2 9或 30个氨基酸为信号肽。胞外区含6 96个氨基酸 ,与病毒的吸附和进入细胞有关 ,并含有多个中和表位。跨膜区含 6 9个氨基酸 ,通过 3个疏水性区段插入膜中。胞浆区 Human herpesvirus type 1 (HHV 1) glycoprotein B is a transmembrane glycoprotein whose precursor molecule contains 904 amino acids. Depending on the strain, the N-terminal 29 or 30 amino acids are signal peptides. The extracellular region contains 6 to 96 amino acids, is involved in virus adsorption and entry into cells and contains multiple neutralizing epitopes. The transmembrane region contains 69 amino acids and is inserted into the membrane through three hydrophobic segments. Cytoplasmic region