妊娠期母系统性红斑狼疮(SLE) 通常认为,妊娠能使SLE恶化。近来,已有异议。作者发现,妊娠期10%～15%SLE病例恶化,产后未见加重。器官系统损害 1.血小板活动性SLE引起的血小板减少通常对皮质类固醇治疗有效。母血小板减少症的治疗取决于其病因。如果有SLE活动的其他表现如面部和手掌红斑,膝关节腔少量渗出液,蛋白尿或低补体血等,或以前该病发作时出现血小板减少或血小板计数≤5万/mm~3,可用强的松30～60mg/日。血板严重减少时为了手术分娩,静脉输注γ-球蛋白能暂时提高血小板计数。必要时最后采取脾切除术。 2.肾脏妊娠不能改变活动性SLE的 Pregnancy SLE generally believes that pregnancy can worsen SLE. Recently, there have been objections. The authors found that 10% to 15% of pregnant women with SLE exacerbations, no increase after delivery. Organ System Damage 1. Thrombocytopenia SLE-induced thrombocytopenia is usually effective for corticosteroid therapy. The treatment of thrombocytopenia depends on its etiology. If there are other manifestations of SLE activity such as facial and palpable erythema, a small amount of knee joint exudate, proteinuria or hypocomplementemia, or the onset of the disease before thrombocytopenia or platelet count ≤ 50,000 / mm ~ 3, available Prednisone 30 ~ 60mg / day. Intravenous infusion of gamma globulin temporarily increases platelet count for severe surgical reduction of blood platelets for surgical deliveries. If necessary, take the last splenectomy. 2. Renal pregnancy can not change the activity of SLE