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目的观察单纯雌激素与避孕药干预对人工流产术后经期及子宫内膜厚度的影响。方法选取2014年7月至2015年7月68例人工流产术患者为研究对象,将患者抽签随机分为观察组与对照组,每组34例。两组均给予基础治疗,对照组行补佳乐(单纯雌激素)干预,观察组行复方口服避孕药优思明(雌激素联合孕激素)干预,观察两组阴道出血情况、平均阴道出血天数、首次月经转归时间、子宫内膜平均厚度、尿妊娠试验转阴率、并发症及不良反应发生率。结果观察组平均阴道出血天数[(5.3±1.2)d]、首次月经转归时间[(27.1±1.3)d]短于对照组[(7.3±1.3)、(31.7±2.6)d],子宫内膜平均厚度[(6.2±1.3)mm]高于对照组[(4.0±2.0)mm],差异有统计学意义(P<0.05)。观察组阴道出血情况优于对照组,术后并发症发生率(2.94%)与不良反应发生率(11.76%)低于对照组(20.59%、35.3%),差异有统计学意义(P<0.05)。结论避孕药优思明中雌激素联合孕激素能缩短阴道出血及首次月经转归时间,减少术后出血量,增加子宫内膜厚度,治疗效果优于单纯使用雌激素且能减少术后总并发症与不良反应发生率。
Objective To observe the effects of estrogen alone and contraceptives on menstrual period and endometrial thickness after induced abortion. Methods A total of 68 cases of induced abortion patients from July 2014 to July 2015 were selected as the study subjects. Patients were randomized into observation group and control group, with 34 patients in each group. The two groups were given basic treatment, the control group received naloxone (estrogen only) intervention, the observation group compound oral contraceptives Yas Ming (estrogen combined with progesterone) intervention to observe the two groups of vaginal bleeding, the average number of days of vaginal bleeding , The first menstruation outcome time, the average thickness of the endometrium, urinary pregnancy test negative rate, complications and adverse reactions. Results The average number of days of vaginal bleeding in the observation group [(5.3 ± 1.2) d] was significantly shorter than that in the control group [(7.3 ± 1.3), (31.7 ± 2.6) d] The average thickness of the membrane was (6.2 ± 1.3) mm higher than that of the control group (4.0 ± 2.0) mm, the difference was statistically significant (P <0.05). The vaginal bleeding in the observation group was better than that in the control group, and the incidence of postoperative complications (2.94%) and adverse reactions (11.76%) were lower than those in the control group (20.59%, 35.3%) ). Conclusion Estrogen contraceptives estrogen combined with progesterone can shorten the vaginal bleeding and the first menstruation prognosis, reduce the amount of postoperative bleeding and increase the thickness of the endometrium, the treatment is better than the simple use of estrogen and can reduce the total postoperative complications Symptoms and adverse reaction rates.