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雪上一支蒿(Aconitum brachypodum Diels)服之过量易引起中毒。临床抢救中应用氢化可的松及阿托品再加上输液,疗效甚好。为此进行了实验。将雪上一支蒿研细,加白酒18℃浸泡8天,过滤,滤液折合生药500mg/ml。家兔以相当于生药50mg/kg的药液由耳缘静脉给予药,造成中毒。当心电图出现窦性停搏即进行抢救。抢救药物同样由耳缘静脉给予。生理盐水组每兔给予生理盐水20ml。氢化可的松组每兔给药123.45mg/m~2用生理盐水稀释至20ml注射。阿托品组一半兔给药1.235mg/m~2,另一半兔给药1.85mg/m~2,同样用生理盐水稀释到20ml注射。实验结果:(1)生理盐水组:家兔中毒后即出现呼吸困难、发绀、潮式呼吸、抽搐、瞳孔散大。典型心
Excessive consumption of Aconitum brachypodum Diels can cause poisoning. Clinical rescue with hydrocortisone and atropine plus infusion, the effect is very good. For this experiment. The snow on a fine study of Artemisia, add white wine soaked in 18 ℃ 8 days, filtered, the filtrate equivalent to crude drug 500mg / ml. Rabbits to the equivalent of crude drug 50mg / kg by the ear vein medicine, resulting in poisoning. When electrocardiogram sinus arrest occurs that rescue. Salvage drugs are also given by the ear vein. Saline group was given normal saline 20ml. Hydrocortisone group of rabbits administered 123.45mg / m ~ 2 diluted with saline to 20ml injection. Atropine group, half of rabbits administered 1.235mg / m ~ 2, the other half of rabbits administered 1.85mg / m ~ 2, also diluted with saline to 20ml injection. Experimental results: (1) saline group: rabbits poisoning occurs after breathing difficulties, cyanosis, tidal breathing, convulsions, mydriasis. Typical heart