论文部分内容阅读
环氧酸酯缩合作用通常在无水条件下进行,不能在应用氢氧化钠水溶液的相转移催化条件下进行。因为卤代酸酯在此情况下发生水解。M.Makosza在无水碳酸钾和18-冠醚-6的两相体系中合成了2-苯基环氧酸乙酯,b.p.99-109℃/0.5mmHg产率72％。
Epoxy ester condensation is usually carried out under anhydrous conditions and can not be carried out under phase transfer catalysis using aqueous sodium hydroxide. Because the haloacid ester is hydrolyzed in this case. M. Makosza synthesized ethyl 2-phenyl-oxalate in a two-phase system of anhydrous potassium carbonate and 18-crown-6, b. Yield 72% at 99-109 ° C / 0.5 mmHg.