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本文采用重用大黄中西医结合治疗出血坏死性胰腺炎２５例，结果提示：有效１９例，有效率７６％；手术４例，手术率１６％；死亡６例，死亡率２４％。与单纯用西药治疗相比较，可减少并发症，降低手术率与死亡率；实验研究结果：①从大黄中找到了８个有效单体对胰蛋白酶等多种胰酶具有明显抑制作用，初步找到了大黄治疗急性胰腺炎的物质基础；②建立和改进了４种动物模型，从亚细胞水平阐明了大黄对胰腺细胞有直接的保护作用。在电镜下观察到胰腺细胞的修复及紧密连接处恢复正常。同时根据大黄对内毒素血症、血液流变性前列腺素、血栓素、厌氧杆菌等多方面的作用，阐明了大黄防治胰腺炎的间接作用。
In this paper, the re-use of Chinese traditional Chinese medicine in the treatment of hemorrhagic necrotizing pancreatitis in 25 cases, the results suggest that: effective in 19 cases, effective rate of 76%; surgery in 4 cases, surgery rate of 16%; 6 deaths, the mortality rate of 24%. Compared with the simple western medicine treatment, the complication can be reduced and the operation rate and the mortality rate can be reduced. Experimental results: (1) Eight effective monomers were found to inhibit trypsin and other trypsin, Rhubarb material basis for the treatment of acute pancreatitis; ② established and improved four animal models, from the subcellular level to clarify the rhubarb has a direct protective effect on pancreatic cells. Pancreatic cells were observed under electron microscope repair and tight junction back to normal. At the same time, according to rhubarb on endotoxemia, blood rheological prostaglandin, thromboxane, anaerobic bacilli and other aspects of the role of elucidation of the indirect effect of rhubarb in the prevention and treatment of pancreatitis.