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对上海市９所医院的２０００例胃癌前变化进行胃镜随访研究。随访时间：第一部分从１９８６年１月～１９９０年３月；第二部分从１９８６年１月～１９９３年６月。随访组每６～１２个月定期复查胃镜，对照组不进行主动胃镜检查，以积分法观察癌前变化。结果：第一部分随访组胃癌发生率为１．８７％（１７／９０９），其中早期胃癌占７０．６％（１２／１７）；对照组胃癌发生率为１．２５％（９／７２１），其中早期胃癌占１１．１％（１／９）。随访组病理积分从４．２５降至２．９５。第二部分仅发现１例早期胃癌（１／２６１）。本研究提示，加强对胃癌高危人群的胃镜随访是早期发现胃癌的有效方法。
A follow-up study of gastroscopy was performed on 2000 precancerous changes in 9 hospitals in Shanghai. Follow-up time: The first part was from January 1986 to March 1990; the second part was from January 1986 to June 1993. The gastroscopes were regularly reviewed every 6-12 months in the follow-up group, and no active gastroscopy was performed in the control group. Precancerous changes were observed by the integral method. RESULTS: The incidence of gastric cancer in the first follow-up group was 1.87% (17/909), of which 70.6% (12/17) were early-stage gastric cancer, and 1.25% (9/721) of gastric cancer in the control group. Among them, early gastric cancer accounted for 11.1% (1/9). Follow-up group pathological score decreased from 4.25 to 2.95. The second part found only 1 case of early gastric cancer (1/261). This study suggests that enhanced gastroscopy for high-risk gastric cancer is an effective method for early detection of gastric cancer.