神经干细胞(NSCs)是指具有自我更新能力,多向分化潜能力,并具有提供一定量脑组织能力的一组细胞群。近年来,NSCs的研究已经成为了神经生物学研究的一个热点。研究人员试图将NSCs移植治疗包括帕金森病(PD)在内的神经系统临床疾病,并且在动物模型中已经取得了一定的成果。现就NSCs的特点、NSCs移植治疗PD的策略以及移植过程中的常见难题等予以综述。 Neural stem cells (NSCs) are a group of cell populations that have self-renewal, multidirectional differentiation potential and have the capacity to provide a certain amount of brain tissue. In recent years, the research of NSCs has become a hot research in neurobiology. Researchers have attempted to transplant NSCs to treat the clinical nervous system diseases including Parkinson’s disease (PD) and have achieved some results in animal models. Now on the characteristics of NSCs, NSCs transplantation for the treatment of PD, as well as the transplant process of the common problems are reviewed.