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摘要目的使用非模型半定量参数评估正常人和哮喘病人肺动态对比增强MR成像(DCE-MRI)对比剂的动力学特征以及探讨肺功能检查与嗜酸性粒细胞水平之间的关系。材料与方法本研究已经过国家研究伦理委员会批准(参考no.11/NW/0378),所有病人均签署书面同意。10例健康受试者和30例哮喘病人在7 d内进行了肺功能检查、血液和痰液嗜酸性粒细胞计数以及1.5 T DCE-MR检查。利用相对信
Abstract Objective To evaluate the kinetic characteristics of pulmonary dynamic contrast-enhanced MR imaging (DCE-MRI) contrast agent in normal and asthmatic patients using non-model semi-quantitative parameters and to explore the relationship between pulmonary function test and eosinophil level. Materials and Methods This study was approved by the National Research Ethics Committee (Ref no.11 / NW / 0378) and all patients have signed written consent. Pulmonary function tests, blood and sputum eosinophil counts, and 1.5 T DCE-MR were performed in 10 healthy subjects and 30 asthmatics within 7 days. Use relative letters