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无合并症的急性肾盂肾炎(AUPN)是成年妇女常见的感染性疾病之一,最常用的治疗药物是氨基糖甙类与氨苄青霉素联合应用。本文比较了氨苄青霉素(Amp)加庆大霉素(GM)与复方新诺明(TMP/SMZ)加 GM 治疗 AUPN 的效果。85名确诊为 AUPN 的妇女(91%为大肠杆菌感染,其余为 G~-菌一种或几种混合感染,仅1例为 G~+菌感染)随机分为两组,一组44例接受 Amp 静注1g/6h,3天后改用口服疗
Acute pyelonephritis without complications (AUPN) is one of the common infectious diseases in adult women. The most commonly used treatment is aminoglycosides in combination with ampicillin. This article compared the effects of ampicillin (Amp) plus gentamicin (GM) with TMP / SMZ plus GM on AUPN. A total of 85 women diagnosed with AUPN (91% infected with Escherichia coli and the remaining G ~ - one or more mixed infections, only 1 patient infected with G ~ +) were randomized into two groups and 44 patients Amp intravenous 1g / 6h, 3 days to switch to oral therapy