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消炎痛为非甾体抗炎药,具有消炎、镇痛、解热作用,临床常用于治疗风湿性及类风湿性关节炎、急性痛风及癌性发热等疾患。近年来发现此药具有抑制前列腺素合成的作用,从而使其临床应用范围有所扩大。现将消炎痛的新用途简要介绍如下,以供临床参考。一、急慢性肾小球肾炎由于消炎痛能抑制前列腺素合成,并有对抗缓激肽,抑制白细胞趋化和稳定溶酶体、抗血小板聚集的作用。因此,临床有用于治疗急慢性肾小球肾炎的报道。天等县人民医院内儿
Indomethacin as non-steroidal anti-inflammatory drugs, with anti-inflammatory, analgesic, antipyretic effect, commonly used in clinical treatment of rheumatic and rheumatoid arthritis, acute gout and cancerous fever and other diseases. In recent years, this drug has been found to inhibit the prostaglandin synthesis and thus its clinical application has been expanded. The new use of indomethacin is briefly described below for clinical reference. First, acute and chronic glomerulonephritis Because indomethacin can inhibit prostaglandin synthesis, and have antagonistic bradykinin, inhibit leukocyte chemotaxis and stable lysosome, anti-platelet aggregation effect. Therefore, clinically useful for the treatment of acute and chronic glomerulonephritis reported. Tian County People’s Hospital children