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本文评价了漂浮式碘缓释器防治地方性甲状腺肿6个月的现场疗效,结果提示:地方性甲状腺肿大率虽有下降,但较对照组未出现统计学差异(P>0.05);防治地方性甲状腺肿有效率和治愈率分别为6.8%和11.0%,较对照组有非常显著的差异(P<0.01);学龄儿童指尖全血T4的均值水平由53.1ng/ml提高到62.3ng/ml,与防治前和同期对照组比较均有非常显著差异(P<0.01),其T4低于正常的异常检出率明显低于对照组(P<0.05);TSH的均值水平防治前后未有明显差异(P>0.05),但对照组的均值和异常检出率均显著高于防治组(P<0.01);尿碘呈现出稳步上升趋势,在1个月时较基础值(81.7μg/L)提高1.4倍,在3个月时(102.4μg/L)提高1.76倍,在6个月时(188.4μg/L)提高3.24倍。以上结果表明,漂浮式碘缓释器对防治IDD具有简便易行、效果可靠、成本低和检测方便等优点,在边远的农牧区和碘盐不能推广的地区使用是理想的方法。
This article evaluated the floating iodine sustained release device prevention and treatment of endemic goiter for 6 months on-site efficacy, the results suggest that: although endemic goiter rate decreased, but no significant difference compared with the control group (P> 0.05) ; The effective rate and the cure rate of endemic goiter prevention and treatment were 6.8% and 11.0%, respectively, which were significantly different from those in the control group (P <0.01). The mean level of T4 in the finger-tip children 53.1ng / ml to 62.3ng / ml, which were significantly different from those of the control group before and at the same period (P <0.01). The detection rate of T4 below normal was significantly lower than that of the control group (P <0.05). There was no significant difference between before and after the mean level of TSH (P> 0.05), but the mean and abnormal detection rate of the control group were significantly higher than that of the control group (P <0.01) Iodine showed a steady upward trend with a 1.4-fold increase at 1 month from baseline (81.7 μg / L) and a 1.76-fold increase at 3 months (102.4 μg / L) (188.4μg / L) increased 3.24 times. The above results show that the floating iodine slow release device has the advantages of simple and convenient control, reliable effect, low cost and convenient detection in the prevention and treatment of IDD. It is an ideal method to be used in remote agricultural and pasturing areas and areas where iodized salt can not be popularized.