百日咳是小儿常见的急性呼吸道传染病,其主要特征为陈发性痉挛性咳嗽,最后伴有鸡呜样回音。该病与一般传染病不同,新生儿、婴儿也可得病。一般年龄越小,病情越严重,病死率也越高。病因和发病机制病原体:百日咳杆菌。发病机制:目前认为百日咳的发病不单是致病菌的问题,而是决定于机体的反应性。机体感染百日咳后,感染自上呼吸道向下蔓延, Pertussis is a common acute respiratory infection in children. Its main characteristic is cough of invigorating spasms. Finally, there is a humming echo. The disease is different from the general infectious diseases, newborns, infants can also get sick. The younger the general age, the more serious the disease, the higher the case fatality rate. Etiology and pathogenesis Pathogen: Bordetella pertussis. Pathogenesis: At present, the incidence of whooping cough is not only a problem of pathogens, but rather the body’s reactivity. After the body infected with pertussis, the infection spreads downward from the upper respiratory tract,