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目的 探讨良性前列腺增生症(BPH)经尿道前列腺电切术(TURP)不同时机的疗效.方法 选取BPH患者100例,进行多普勒超声检查,按照膀胱壁形态及残余尿量将其分为代偿期组和失代偿期组,每组50例.分别观察两组患者术前和术后1,3个月的前列腺症状评分(IPSS)、最大尿流率(Qmax)、生活质量(QOL)评分、前列腺体积,评价其临床疗效.结果 代偿期组和失代偿期组患者IPSS由术前的(25.74±4.28)、(26.52±5.12)分,分别下降至术后1,3个月的(9.42±3.05)、(12.47±3.30)分和(5.04±1.86)、(11.36±2.35)分,Qmax由术前的(4.52± 1.57)、(4.15±2.05) ml/s,分别增加至术后1,3个月的(13.24±2.98)、(10.25±3.25) ml/s和(15.72±3.18)、(11.65±2.74) ml/s,QOL评分由术前的(5.07±1.34)、(5.56±1.43)分,分别下降至术后1,3个月的(1.94±0.51)、(3.07±0.62)分和(1.24±0.26)、(2.52±0.29)分,前列腺体积由术前的(62.72±7.23)、(64.81±8.42)cm3,分别下降至术后1,3个月的(25.75±6.22)、(26.80±7.14)cm3和(26.19±4.78)、(27.24±3.76) cm3.术后1,3个月与术前、术后1个月两组间及术后3个月两组间IPSS、Qmax、QOL评分比较差异均有统计学意义(P＜0.05).结论 TURP能明显改善BPH患者症状,及早手术治疗的患者术后临床疗效确切,病情恢复快,能减少患者的痛苦及经济损失.“,”Objective To investigate the curative effect of different timing of transurethral resection of prostate (TURP) in the treatment of benign prostate hyperplasia (BPH).Methods One hundred patients with BPH were examined by the Doppler ultrasound,the patients were divided into compensation period group and decompensation period group according to the bladder wall form and residual urine volume with 50 cases each.The international prostate symptom score (IPSS),maximum flow rate (Qmax),quality of life (QOL) score and prostate volume in the 2 groups were observed preoperative,postoperative 1,3 months after operation,then to evaluate the clinical curative effect.Results In compensation period group and decompensation period group,IPSS decreased from preoperative (25.74 ± 4.28) and (26.52 ± 5.12) scores to postoperative 1,3 months (9.42 ± 3.05) and (12.47 ± 3.30) scores,(5.04 ± 1.86) and (11.36 ± 2.35) scores.Qmax increased from preoperative (4.52 ± 1.57) and (4.15 ± 2.05) ml/s to postoperative 1,3 months (13.24 ± 2.98) and (10.25 ± 3.25) ml/s,(15.72 ± 3.18) and (11.65± 2.74) ml/s.QOL score decreased from preoperative (5.07 ± 1.34) and (5.56 ± 1.43) scores to postoperative 1,3 months (1.94 ± 0.51) and (3.07 ± 0.62) scores,(1.24 ± 0.26) and (2.52 ± 0.29) scores.Prostate volume decreased from preoperative (62.72 ± 7.23) and (64.81 ± 8.42) cm3 to postoperative 1,3 months (25.75 ± 6.22) and (26.80 ± 7.14)cm3,(26.19 ± 4.78) and (27.24 ± 3.76) cm3.There were significant differences of IPSS,Qmax,QOL score between postoperative 1,3 months and preoperative,and between the 2 groups postoperative 1,3 months (P ＜ 0.05).Conclusion TURP can obviously improve the symptoms of patients with BPH,patients of early surgical treatment have definite clinical curative effect and fast recovery,early surgical treatment can reduce the pain of the patients and the economic losses.