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人体感染疟疾以后,可以获得一定的免疫力,这是在很早以前就知道的事实。但是用血清检验的方法,具体测定疟疾抗体的存在,是从六十年代才开始的。Tobie 及 Coa-tncy(1961)报告,一名实验室工作人员偶然感染 P.cynomolgi(B 株),发病14天后有荧光抗体反应。Kuvin 等(1962)报告,对二例间日疟患者的连续观察,发现在周围血液中查到原虫后,随即可见抗体出现;抗体滴度增加很快,1例最高达1∶2560,1例1∶320。经治疗原虫消失后,抗体仍维持至感染后两个月,然后逐渐下降,至121天
After the human body was infected with malaria, some immunity can be obtained, which is a fact known long ago. However, the serum test method, the specific determination of the presence of malaria antibodies, only from the sixties. Tobie and Coa-tncy (1961) reported that a laboratory worker accidentally infected P.cynomolgi (strain B) with a fluorescent antibody response 14 days after onset. Kuvin et al. (1962) reported continuous observation of two cases of Plasmodium falciparum and found that antibodies appeared immediately after the parasite was found in the peripheral blood. Antibody titers increased very rapidly in 1 case up to 1 in 2560 and in 1 case 1: 320. After the disappearance of the treated protozoa, the antibody was maintained until two months after infection, and then gradually decreased to 121 days